Which prefix indicates something related to the head?

The prefix that indicates something related to the head is "cephalo-." This term is derived from the Greek word "kephalē," which directly means "head." It is commonly used in medical terminology to describe structures, conditions, or procedures associated with the head. For example, "cephalalgia" refers to a headache, indicating pain in the head area. The precision of this prefix is essential in medical practices, as it helps healthcare professionals accurately describe locations and conditions related to the cranial region.

Other prefixes, while related to different body systems or regions, do not specifically denote the head. The prefix related to the nervous system is "neuro-," which pertains to nerves and the brain but not specifically to the head itself. "Oculo-" pertains to the eye, and "dermato-" refers to the skin, neither of which relates directly to the head. Therefore, "cephalo-" is the correct choice for anything associated with the head.